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Low-invasive somatic oncogenes and lymph node metastasis in pediatric papillary thyroid cancer: implications for prophylactic central neck dissection.

Julia A BaranMya BojarskyStephen HaladaJulio C Ricarte-FilhoAmber IsazaAime T FrancoLea F SurreyTricia BhattiZubair BalochN Scott AdzickSogol Mostoufi-MoabKen KazahayaAndrew J Bauer
Published in: European thyroid journal (2024)
Pediatric patients with low-invasive somatic oncogenic alterations are at low risk for metastasis to central neck LNs. Our findings suggest that preoperative knowledge of somatic oncogene alterations provides objective data to stratify pediatric patients who may not benefit from pCND.
Keyphrases
  • lymph node metastasis
  • copy number
  • squamous cell carcinoma
  • healthcare
  • patients undergoing
  • electronic health record
  • big data
  • papillary thyroid
  • gene expression
  • machine learning
  • artificial intelligence
  • data analysis