Association of circulating metabolites in plasma or serum and risk of stroke: Meta-analysis from seven prospective cohorts.

Dina VojinovicMarita KalaojaStella TrompetKrista FischerMartin J ShipleyShuo LiAki S HavulinnaMarkus PerolaVeikko SalomaaQiong YangNaveed SattarPekka JousilahtiNajaf AminClaudia L SatizabalNele TabaBehnam SabayanRamachandran S VasanM Arfan IkramDavid J StottMika Ala-KorpelaJ Wouter JukemaSudha SeshadriJohannes KettunenMika KivimakiTonu EskoCornelia M van Duijn

Published in: Neurology (2020)

We found association of amino acids, glycolysis-related metabolites, acute phase reaction markers, and several lipoprotein subfractions with the risk of stroke. These findings support the potential of metabolomics to provide new insights into the metabolic changes preceding stroke.

Keyphrases

atrial fibrillation
systematic review
ms ms
amino acid
cerebral ischemia
risk assessment
climate change
case control