Schizophrenia predisposition gene Unc-51-like kinase 4 for the improvement of cerebral ischemia/reperfusion injury.
Wen LuoJunqing YangPublished in: Molecular biology reports (2022)
ULK4 protects against CIRI, and the underlying mechanism involves PI3K pathway activation which in turn inhibits apoptosis.
Keyphrases
- ischemia reperfusion injury
- oxidative stress
- bipolar disorder
- endoplasmic reticulum stress
- cell cycle arrest
- subarachnoid hemorrhage
- copy number
- genome wide
- fluorescent probe
- cell death
- sensitive detection
- living cells
- protein kinase
- genome wide identification
- tyrosine kinase
- cerebral ischemia
- brain injury
- quantum dots
- dna methylation
- cerebral blood flow
- transcription factor