Variation in treatment and survival of older patients with non-metastatic breast cancer in five European countries: a population-based cohort study from the EURECCA Breast Cancer Group.
Marloes G M DerksEsther BastiaannetMandy KiderlenDenise E HillingPetra G BoelensPaul M WalshElizabeth van EyckenSabine SieslingJohn BroggioLynda WyldMaciej TrojanowskiAgnieszka KolacinskaJustyna Chalubinska-FendlerAna Filipa GonçalvesTomasz NowikiewiczWojciech ZegarskiRiccardo A AudisioGerrit-Jan LiefersJohanneke E A PortieljeCornelis J H van de Veldenull nullPublished in: British journal of cancer (2018)
There is substantial variation in treatment strategies and survival outcomes in elderly with BC in Europe. For early-stage BC, we observed large variation in endocrine therapy but no variation in relative survival, suggesting potential overtreatment. For advanced BC, we observed higher survival in countries with lower proportions of omission of surgery, suggesting potential undertreatment.