Anti-TNFα treatment in Crohn's disease: Impact on hepatic steatosis, gut-derived hormones and metabolic status.

Paul MankaSvenja SydorNishikant WaseJan BestMalte BrandenburgAnnika HellbeckJulia SchänzerRamiro Vilchez-VargasAlexander LinkAnja FiggeAndreas JähnertUlrike von ArnimJason D CoombesFrancisco-Javier CuberoAlisan KahramanMoon-Sung KimJulia KälschSonja KinnerKlaas-Nico FaberHan MoshageGuido GerkenWing-Kin SynScott L FriedmanPeter LemmerLars P Bechmann

Published in: Liver international : official journal of the International Association for the Study of the Liver (2021)

Anti-TNFα treatment is associated with reduced steatosis, lower triglyceride levels, alterations in FXR-signalling (eg FGF19) and microbiota composition in CD.

Keyphrases

rheumatoid arthritis
insulin resistance
metabolic syndrome
combination therapy
adipose tissue
skeletal muscle