Renal insulin resistance in type 2 diabetes mellitus and progression of chronic kidney disease: potential pathogenic mechanisms.

Alrataj AlqallafPatrick SwanNeil G Docherty

Published in: Expert review of endocrinology & metabolism (2022)

Measurement of insulin sensitivity may add value to profiling of renal risk in T2DM. Rational selection of therapeutic strategies targeting the enhancement of insulin sensitivity merits special attention regarding the personalized management of CKD in insulin resistance predominant T2DM.

Keyphrases

insulin resistance
chronic kidney disease
end stage renal disease
adipose tissue
high fat diet

glycemic control
metabolic syndrome
type diabetes
polycystic ovary syndrome
skeletal muscle

high fat diet induced
working memory
single cell
cancer therapy

drug delivery
peritoneal dialysis
weight loss
breast cancer risk