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Pregnancy and neonatal outcomes in women receiving calcineurin inhibitors: A systematic review and meta-analysis.

Shintaro AkiyamaShadi HamdehNaoka MurakamiThomas G CotterHideo SuzukiKiichiro Tsuchiya
Published in: British journal of clinical pharmacology (2022)
Given the higher mortalities in CNI-treated patients and their children than the general averages, their pregnancy is considered high risk. The risks of preterm delivery and low birth weight were primarily attributed to preeclampsia. Since prepregnancy hypertension increased its risk, an appropriate preconception blood pressure management may improve their outcomes.
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