Zanthoxylum zanthoxyloides Alkaloidal Extract Improves CCl4-Induced Hepatocellular Carcinoma-Like Phenotypes in Rats.

Desmond Omane AcheampongIsaac Kyei BaffourVictor Yao Atsu BarkuJustice Kwaku AddoMainprice Akuoko Essuman Alex Boye

Published in: Evidence-based complementary and alternative medicine : eCAM (2021)

ZZAE ameliorated CCl4/olive oil-induced HCC-like phenotype in rats and demonstrated general hepatoprotective effects by improving liver and kidney function markers. This finding rationalizes the need for further studies on ZZAE as a potential source of bioactive anti-HCC compounds.

Keyphrases

high glucose
drug induced
liver injury
diabetic rats
oxidative stress
endothelial cells