RSK3 switches cell fate: from stress-induced senescence to malignant progression.

Anda HunaJean-Michel FlamanCatalina LodillinskyKexin ZhuGabriela MakulyteVictoria PakulskaYohann CouteClémence RuisseauxPierre SaintignyHector Hernandez-VargasPierre-Antoine DefossezMathieu BoissanNadine MartinDavid Bernard

Published in: Journal of experimental & clinical cancer research : CR (2023)

We conclude that RSK3 switches cell fate from senescence to malignancy in response to TGFβ signaling.

Keyphrases

cell fate
stress induced
transforming growth factor
endothelial cells
epithelial mesenchymal transition
signaling pathway