Clinic-based evaluation of the dual Xpert CT/NG assay on the GeneXpert System for screening for extragenital chlamydial and gonococcal infections amongst men who have sex with men.
Maddalena CordioliLorenzo GiosAnna ErbogastoMassimo MirandolaAngela SandriValeska PadoveseCarlos CaceresSilver VargasKarel BlondeelRonaldo SilvaJames KiarieFirdavs KurbonovRosanna W PeelingSoe Soe ThwinDaniel GolparianMagnus UnemoIgor Toskinnull nullPublished in: BMC infectious diseases (2024)
Rapid turnaround time, ease of use and high acceptability make the Xpert CT/NG testing system a strategic tool for increasing testing frequency, reaching those not yet tested and offering the possibility of immediate treatment if needed. The assay showed good negative likelihood ratios and confirms its use to rule out CT/NG infections. Sensitivity varied across sites and pathogens. Periodic staff training at the testing sites should be mandatory.
Keyphrases
- men who have sex with men
- image quality
- dual energy
- computed tomography
- contrast enhanced
- hiv testing
- hiv positive
- high throughput
- positron emission tomography
- primary care
- magnetic resonance imaging
- gram negative
- antimicrobial resistance
- multidrug resistant
- south africa
- antiretroviral therapy
- human immunodeficiency virus
- pet ct
- replacement therapy
- quantum dots
- virtual reality