Functional imaging of mitochondria in genetically confirmed retinal dystrophies using flavoprotein fluorescence.

Matthew W RussellJustin C MusteKanika SethMadhukar KumarCollin A RichRishi P SinghElias I Traboulsi

Published in: Ophthalmic genetics (2022)

FPF intensity and heterogeneity significantly increased in patients with retinal dystrophies. The correlation of FPF lesions with FAF lesions implies FPF may be a clinically useful biomarker in patients with IRDs.

Keyphrases

optical coherence tomography
diabetic retinopathy
optic nerve
high resolution
single cell
high intensity
cell death
reactive oxygen species