Mutations Status of NOTCH Signaling Pathway Predict Prognosis of Immune Checkpoint Inhibitors in Colorectal Cancer.

Anqi LinJiarong Yao Quan ChenZaoqu LiuPeng LuoJian Zhang

Published in: Journal of inflammation research (2023)

NOTCH-MT status was strongly associated with the prognosis of CRC patients treated with ICIs and is expected to serve as a novel biomarker and therapeutic target for CRC.

Keyphrases

signaling pathway
cell proliferation
epithelial mesenchymal transition
oxidative stress
induced apoptosis
endoplasmic reticulum stress