Overview of Ocular Side Effects of Selinexor.
Nagham Al-ZubidiDan S GombosDavid S HongVivek SubbiahSiqing FuJordi Rodon AhnertSarina A Piha-PaulApostolia M TsimberidouDaniel D KarpFunda Meric BernstamAung NaingPublished in: The oncologist (2021)
Patients receiving selinexor in combination with multiple standard chemotherapy or immunotherapy agents were reviewed, with a total of 34 patients experiencing 37 ocular adverse events. Findings highlight that ocular adverse events associated with oral selinexor were mild. The most frequently reported ocular treatment-related adverse events were mild dry eye and progression of age-related nuclear sclerosis. None of the ocular adverse events required therapy discontinuation.