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Overview of Ocular Side Effects of Selinexor.

Nagham Al-ZubidiDan S GombosDavid S HongVivek SubbiahSiqing FuJordi Rodon AhnertSarina A Piha-PaulApostolia M TsimberidouDaniel D KarpFunda Meric BernstamAung Naing
Published in: The oncologist (2021)
Patients receiving selinexor in combination with multiple standard chemotherapy or immunotherapy agents were reviewed, with a total of 34 patients experiencing 37 ocular adverse events. Findings highlight that ocular adverse events associated with oral selinexor were mild. The most frequently reported ocular treatment-related adverse events were mild dry eye and progression of age-related nuclear sclerosis. None of the ocular adverse events required therapy discontinuation.
Keyphrases
  • optic nerve
  • end stage renal disease
  • ejection fraction
  • squamous cell carcinoma
  • mesenchymal stem cells
  • radiation therapy
  • optical coherence tomography
  • patient reported
  • chemotherapy induced