Complex Epigenetic Regulation of Chemotherapy Resistance and Biohlogy in Esophageal Squamous Cell Carcinoma via MicroRNAs.

Kirsten LindnerAnn-Kathrin EichelmannChristiane MatuszcakDamian James Hussey Joerg HaierRichard Hummel

Published in: International journal of molecular sciences (2018)

Our data present strong evidence that specific microRNA signatures are responsible for drug resistance and aggressiveness of ESCC. Final functional readout of these complex processes appears to be more important than single microRNA-target interactions.

Keyphrases

electronic health record
genome wide
locally advanced
gene expression
squamous cell carcinoma
machine learning
deep learning
artificial intelligence