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Identification of potential autophagy-related genes in steroid-induced osteonecrosis of the femoral head via bioinformatics analysis and experimental verification.

Xue-Zhen LiangDi LuoYan-Rong ChenJia-Cheng LiBo-Zhao YanYan-Bo GuoMing-Tao WenBo XuGang Li
Published in: Journal of orthopaedic surgery and research (2022)
Thirty-four potential autophagy-related genes involved in SONFH were identified via bioinformatics analysis. TNFSF10, PTEN and BCL2L1 might serve as potential drug targets and biomarkers because they regulate autophagy. These results expand the autophagy-related understanding of SONFH and might be useful in the diagnosis and prognosis of SONFH.
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