The effects of callous-unemotional traits and aggression subtypes on amygdala activity in response to negative faces.
Pascal-M AggensteinerNathalie E HolzBoris W BöttingerSarah BaumeisterSarah HohmannJulia E WerhahnJilly NaaijenShahrzad IlbegiJeffrey C GlennonPieter J HoekstraAndrea DietrichRenee Kleine DetersMelanie C SaamUlrike M E SchulzeDavid J LythgoeArjun SethiMichael C CraigMathilde MastroianniIlyas Sagar-OuriaghliParamala J SantoshMireia RosaNuria BargalloJosefina Castro-FornielesCelso ArangoMaria J PenzolJorge VidalBarbara FrankeMarcel P ZwiersJan K BuitelaarSusanne WalitzaTobias BanaschewskiDaniel BrandeisPublished in: Psychological medicine (2020)
Our results showed differences in amygdala activity and SC responses to emotional faces between cases with ODD/CD and TD, while CU traits moderate both central (amygdala) and peripheral (SC) responses. Our insights regarding subtypes and trait-specific aggression could be used for improved diagnostics and personalized treatment.