Effect of Osimertinib on CTCs and ctDNA in EGFR Mutant Non-Small Cell Lung Cancer Patients: The Prognostic Relevance of Liquid Biopsy.
Galatea KallergiEmmanouil KontopodisAliki NtzifaNúria Jordana-ArizaNiki KarachaliouEvangelia PantazakaHaris A CharalambousAmanda PsyrriEmily TsarouchaIoannis BoukovinasAnna KoumarianouDora HatzidakiEvi S LianidouVassilis GeorgouliasRafael RosellAthanasios ΚotsakisPublished in: Cancers (2022)
The decrease in both CTCs and ctDNA occurring early during osimertinib treatment is predictive of better outcome, implying that liquid biopsy monitoring may be a valuable tool for the assessment of treatment efficacy.