DNA Methylation Signatures Reveal the Diversity of Processes Remodeling Hepatocellular Carcinoma Methylomes.
Léa MeunierThéo Z HirschStefano CarusoSandrine ImbeaudQuentin BayardAmélie RoehrigGabrielle CouchyJean-Charles NaultJosep M LlovetJean-Frédéric BlancJulien CalderaroJessica Zucman-RossiEric LetouzéPublished in: Hepatology (Baltimore, Md.) (2022)
This study elucidates the diversity of processes remodeling HCC methylomes and reveals the epigenetic and transcriptional impact of driver alterations.