Peripheral synucleinopathy in Parkinson disease with LRRK2 G2385R variants.

Jing YangHao WangYanpeng YuanShiheng FanLanjun LiChenyang JiangChengyuan MaoChanghe ShiYu-Ming Xu

Published in: Annals of clinical and translational neurology (2021)

Synucleinopathy is related to the LRRK2 G2385R genotype and implies a different pathogenesis in G2385R variant carriers and noncarriers. This study also extended the clinical profiles of PD patients with the G2385R variant.

Keyphrases

parkinson disease
deep brain stimulation
copy number
gene expression
genome wide