Patients with infusion-related reactions on fixed-dose rituximab treatment have higher body surface area than those without infusion-related reactions in adults with frequently relapsing minimal change nephrotic syndrome: a retrospective study.
Hironobu NishiuraMasaya TakahashiKatsuhito MoriTakashi SugimotoMasanori EmotoYasutaka NakamuraPublished in: Journal of pharmaceutical health care and sciences (2024)
Our study revealed that adults with frequently relapsing MCNS who experienced IRRs tend to have a higher BSA, even with fixed-dose rituximab treatment. Therefore, when patients with higher BSA receive rituximab treatment, clinicians should be careful about monitoring patient condition whether the dosage is fixed or not.