In Vivo 6-([18F]Fluoroacetamido)-1-hexanoicanilide PET Imaging of Altered Histone Deacetylase Activity in Chemotherapy-Induced Neurotoxicity.
Nobuyoshi FukumitsuSkye Hsin-Hsien YehLeo Garcia Flores IiUday MukhopadhyayDaniel YoungKazuma OgawaHwan-Jeong JeongWilliam TongJuri George GelovaniPublished in: Contrast media & molecular imaging (2018)
[18F]FAHA PET clearly showed increased HDAC activity suggestive of cisplatin neurotoxicity in vivo, which was blocked by SAHA pretreatment.