Protective effect of the extremolytes ectoine and hydroxyectoine in a porcine organ culture.
Teresa TsaiAna M Mueller-BuehlYathavan SatgunarajahSandra KuehnH Burkhard DickStephanie Christine JoachimPublished in: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie (2020)
Both extremolytes had a protective effect on CoCl2-induced hypoxia in the porcine retina organ culture. Regarding the reduction of hypoxic stress, hydroxyectoine appears to be more effective. Thus, both extremolytes represent an interesting potential new therapeutic approach for patients with ocular diseases in which hypoxic processes play a significant role.