Syndrome of inappropriate anti-diuresis induces volume-dependent hypercalciuria.

J GrellierA JaafarA MartinM El AlaouiC LebelyI TackMarion Vallet

Published in: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA (2017)

Our results show that SIAD results in a volemic expansion tendency that is associated with a decrease in renal calcium reabsorption and thus hypercalciuria, whereas in the hypovolemic group, calciuria was not increased. Therefore, renal loss of calcium and bone demineralization in SIAD patients could be partly induced by volemic expansion.

Keyphrases

end stage renal disease
newly diagnosed
ejection fraction
chronic kidney disease
prognostic factors
peritoneal dialysis
bone mineral density
postmenopausal women
body composition
bone loss
bone regeneration