Manufacturer Signal-to-Cutoff Threshold Underestimates Cumulative Incidence of SARS-CoV-2 Infection: Evidence from the Los Angeles Firefighters Study.
Omar ToubatAnders H BergKimia SobhaniKaren MulliganAcacia M HoriJay BhattacharyaNeeraj SoodPublished in: The journal of applied laboratory medicine (2022)
S/Co thresholds based on known negative samples significantly increase seropositivity and more accurately estimate cumulative incidence of disease compared to manufacturer-based thresholds.
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