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Blinatumomab in pediatric patients with relapsed/refractory B-cell precursor acute lymphoblastic leukemia.

Manon QueudevillePatrick SchlegelAmadeus T HeinzTeresa LenzMichaela DöringUrsula HolzerUlrike HartmannHermann KreyenbergArend von StackelbergMartin SchrappeGerhard ZugmaierTobias FeuchtingerPeter LangRupert HandgretingerMartin Ebinger
Published in: European journal of haematology (2021)
Despite heavy pretreatment of most of our patients, severe adverse events were rare and response rates encouraging. Blinatumomab is a valuable bridging salvage therapy for relapsed or refractory patients to a second or even third HSCT.
Keyphrases
  • acute lymphoblastic leukemia
  • end stage renal disease
  • ejection fraction
  • newly diagnosed
  • allogeneic hematopoietic stem cell transplantation
  • prognostic factors
  • patient reported outcomes