Login / Signup

Use of liquid lithography to form in vitro intestinal crypts with varying microcurvature surrounding the stem cell niche.

R Logan HowardYuli WangNancy L Allbritton
Published in: Journal of micromechanics and microengineering : structures, devices, and systems (2021)
colonic crypts with programmable curvature. Primary cells at the crypt base sensed and responded to surface curvature by altering their proliferation and cytoskeletal properties.
Keyphrases
  • stem cells
  • induced apoptosis
  • cell cycle arrest
  • signaling pathway
  • endoplasmic reticulum stress
  • oxidative stress
  • ulcerative colitis
  • cell death
  • cell therapy