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Immunopathological Mechanisms Underlying Cardiac Damage in Chagas Disease.

Mariana Citlalli de Alba-AlvaradoElia Torres-GutiérrezOlivia Alicia Reynoso-DucoingEdgar Zenteno-GalindoMargarita Cabrera-BravoYolanda Guevara-GómezPaz María Salazar-SchettinoNorma Rivera-FernándezMartha Irene Bucio-Torres
Published in: Pathogens (Basel, Switzerland) (2023)
In Chagas disease, the mechanisms involved in cardiac damage are an active field of study. The factors underlying the evolution of lesions following infection by Trypanosoma cruzi and, in some cases, the persistence of its antigens and the host response, with the ensuing development of clinically observable cardiac damage, are analyzed in this review.
Keyphrases
  • left ventricular
  • oxidative stress
  • trypanosoma cruzi
  • heart failure
  • immune response