Deregulation of desmosomal proteins and extracellular matrix proteases in odontogenic keratocyst.
Marina Gonçalves DinizFilipe Fideles Duarte-AndradeFernanda StussiJéssica Gardone VitórioFelipe Paiva FonsecaRomênia Ramos DominguesAdriana F Paes LemeCarolina Cavaliéri GomesRicardo Santiago GomezPublished in: Oral diseases (2020)
Proteomic analysis strengthened the notion that OKC cells have a similar proteomic profile to oral keratinocytes. Contextual investigation of the differentially expressed proteins revealed the deregulation of desmosome proteins and ECM degradation as important alterations in OKC pathobiology.