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Remote Controlling DNA Hydrogel by Magnetic Field.

Xiaozhou MaZhongqiang YangYijie WangGuoliang ZhangYu ShaoHaoyang JiaTianyang CaoRui WangDongsheng Liu
Published in: ACS applied materials & interfaces (2017)
DNA hydrogel has aroused widespread attention because of its unique properties. In this work, the DNA-modified magnetic nanoparticles were integrated into the mainframe of DNA hydrogel, resulting in DNA-MNP hydrogel. Under the magnetic field, this hydrogel can be remotely deformed into various shapes, driven to jump between two planes and even climb the hill. By applying various triggers, such as temperature, enzyme, and magnetic field, DNA-MNP hydrogel can specifically undergo sol-gel transition. This work not only imparts DNA hydrogel with a new fold of property but also opens a unique platform of such smart materials for its further applications.
Keyphrases
  • circulating tumor
  • drug delivery
  • cell free
  • single molecule
  • hyaluronic acid
  • wound healing
  • tissue engineering
  • nucleic acid
  • magnetic nanoparticles
  • circulating tumor cells
  • high throughput