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Association between HLA gene polymorphisms and mortality of COVID-19: An in silico analysis.

Yusuke TomitaTokunori IkedaRyo SatoTakuro Sakagami
Published in: Immunity, inflammation and disease (2020)
This study suggests that individuals with HLA-A*11:01 or HLA-A*24:02 genotypes may generate efficiently T-cell-mediated antiviral responses to SARS-CoV-2 compared with HLA-A*02:01. The differences in HLA genotypes may potentially alter the course of the disease and its transmission.
Keyphrases
  • sars cov
  • coronavirus disease
  • cardiovascular disease
  • respiratory syndrome coronavirus
  • molecular docking