A strategy of vascular-targeted therapy for liver fibrosis.

Yuan LinMeng-Qi DongZhi-Min LiuMeng XuZhi-Hao HuangHong-Juan LiuYi GaoWei-Jie Zhou

Published in: Hepatology (Baltimore, Md.) (2022)

Liver vascular changes occurred at very early stage of fibrogenesis. Different vessels play different roles in liver fibrosis. The combinational treatment of AAV9-LECT2-shRNA and bevacizumab could significantly improve the therapeutic effects on liver fibrosis.

Keyphrases

liver fibrosis
early stage
metastatic colorectal cancer
replacement therapy