Utility of plasma cell-free DNA detection using homobifunctional imidoesters using a microfluidic system for diagnosing active tuberculosis.

Joung Ha ParkBonhan KooMin Jae KimHyo Joo LeeHye-Hee ChaJi Yeun KimSei Won LeeYong ShinSung Han Kim

Published in: Infectious diseases (London, England) (2021)

Plasma cfDNA assay seems to be a useful adjunct to the current tests for diagnosing TB, especially when used in combination with IGRA for ruling out TB.AbbreviationsTBtuberculosiscfDNAcell-free DNAPCRpolymerase chain reactionAFBacid-fast bacilliIGRAinterferon-gamma releasing assayCTcomputed tomographyHIVhuman immunodeficiency virus.

Keyphrases

mycobacterium tuberculosis
high throughput
label free
pulmonary tuberculosis
circulating tumor cells
hiv aids
loop mediated isothermal amplification
real time pcr
human immunodeficiency virus
hepatitis c virus
hiv infected
adverse drug
electronic health record
antiretroviral therapy
disease virus
drug induced