Optimizing Therapeutic Drug Monitoring in Pregnant Women: a Critical Literature Review.

Fernanda de Lima MoreiraJhohann Richard de Lima BenziLeonardo PintoMatheus de Lucca ThomazGeraldo DuarteVera Lucia Lanchote

Published in: Therapeutic drug monitoring (2022)

More data are needed to support informed benefit-risk decision-making for the administration of drugs to pregnant women. TDM and/or PK studies could ensure that pregnant women receive an adequate dosage of an active drug. Mechanistic modeling approaches potentially could increase our knowledge about the pharmacotherapy of this special population, and they could be used to better design dosage regimens.

Keyphrases

pregnant women
decision making
pregnancy outcomes
healthcare
electronic health record
case report
big data
emergency department
machine learning
deep learning
artificial intelligence
data analysis
breast cancer risk