Various treatment modalities for isolated intracranial middle cerebral arterial dissection with progressive ischemic symptoms: 2 case reports of endovascular stent and bypass surgery.
Chanbo EunHongbum KimSuhee ChoKuhyun YangPublished in: Journal of cerebrovascular and endovascular neurosurgery (2023)
Isolated middle cerebral artery dissection (MCAD) is rare but increasingly recognized as a significant clinical entity, particularly in younger adults. Ischemic stroke is the most common manifestation in symptomatic cases but symptoms can vary in severity from headaches to severe neurologic deficits. Due to its rarity and unpredictable clinical course, there is no established treatment strategy for isolated MCAD. Through two case reports, we reviewed the post-operative clinical course of MCAD under different treatment modalities. Case 1 was a 21-year-old woman who presented to the emergency department with headaches and left-side hemiparesis. Isolated MCAD was diagnosed and she was successfully treated with the placement of a self-expandable stent and subsequent chemical angioplasty for post-stent vasospasm. Case 2 was a 35-year-old woman who presented to the emergency department with left-side hemiparesis and dysarthria. Isolated MCAD was diagnosed and she was successfully treated with superficial temporal artery (STA) to middle cerebral artery (MCA) anastomosis.
Keyphrases
- middle cerebral artery
- emergency department
- internal carotid artery
- subarachnoid hemorrhage
- multiple sclerosis
- minimally invasive
- traumatic brain injury
- combination therapy
- oxidative stress
- stress induced
- acute coronary syndrome
- depressive symptoms
- sleep quality
- ischemia reperfusion injury
- optical coherence tomography
- cerebral ischemia
- smoking cessation
- replacement therapy