Blood Parasite Load as an Early Marker to Predict Treatment Response in Visceral Leishmaniasis in Eastern Africa.
Luka VerrestAnke E KipAhmed M MusaGerard J SchooneHenk D F H SchalligJane MbuiEltahir A G KhalilBrima M YounisJoseph OloboLilian WereRobert KimutaiSéverine MonneratIsra CruzMonique WasunnaFabiana AlvesThomas P C DorloPublished in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America (2021)
Blood Leishmania parasite load determined by qPCR is a promising early biomarker to predict relapse in VL patients. Once optimized, it might be useful in dose finding studies of new chemical entities.