Bioprosthetic Total Artificial Heart in Autoregulated Mode Is Biologically Hemocompatible: Insights for Multimers of von Willebrand Factor.

Bastien PoitierRichard ChocronChristophe PeroninoAurélien PhilippeYuri PyaNadia RivetUlysse RichezMakhabbat S Bekbossynova Nicolas Gendron Marc GrimméMarie Cécile BoriesJulie BrichetAntoine CapelJeanne RancicBenoit Vedie Jean Christian RousselAnne-Sophie JannotPiet JansenAlain CarpentierPeter IvakChristian LatremouilleIvan NetukaDavid M Smadja

Published in: Arteriosclerosis, thrombosis, and vascular biology (2022)

We demonstrated that A-TAH does not cause hemolysis or AWVS. However, relationship between HMWM and cardiac output depending flow confirms relevance of VWF as a biological sensor of blood flow, even in normal range.

Keyphrases

blood flow
mitral valve
aortic valve
aortic valve replacement
left ventricular
heart failure
transcatheter aortic valve replacement
atrial fibrillation
aortic stenosis
transcatheter aortic valve implantation