A controlled-release oral opioid supports S. aureus survival in injection drug preparation equipment and may increase bacteremia and endocarditis risk.
Katherine J KasperIswarya ManoharanBrian HallamCharlotte E ColemanSharon L KoivuMatthew A WeirJohn K McCormickMichael S SilvermanPublished in: PloS one (2019)
14% of all cookers/filters used in the preparation of Hydromorphone-CR were contaminated with S. aureus. Hydromorphone-CR prolongs the survival of MRSA and MSSA in cookers/filters. Heating cookers/filters may be a harm-reduction strategy.