Schistosoma mansoni infection as a trigger to collapsing glomerulopathy in a patient with high-risk APOL1 genotype.
Precil D NevesRamaiane A BridiJanaína A RamalhoLectícia B JorgeElieser H WatanabeAndreia WatanabeLuis YuViktoria WoronikRafaela B PinheiroLeonardo A TestagrossaLívia Barreira CavalcanteDenise Maria Avancini Costa MalheirosCristiane B DiasLuiz Fernando OnuchicPublished in: PLoS neglected tropical diseases (2020)
This is the first report of CG associated with SM in the setting of an HRG. This case highlights the two-hit model as a mechanism for CG pathogenesis, where the high-risk APOL1 genotype exerts a susceptibility role and SM infection serves as a trigger to CG.
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