Is the neuroscientist's grandmother in the notebook? Integrated information and reference frames in the search for consciousness.

This commentary suggests that the physical substrate of integrated information is dependent on the reference frame used to observe it. Furthermore, it uses a thought experiment - can a neuroscientist, locked in a closed room and connected through Zoom with his grandmother to demonstrate that the consciousness of his grannie is NOT in the PC? - to underline the problems that neglecting reference frames may cause to consciousness research.