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Overcoming difficulties with equipoise to enable recruitment to a randomised controlled trial of partial ablation vs radical prostatectomy for unilateral localised prostate cancer.

Daisy ElliottFreddie C HamdyTom A LeslieDerek RosarioTim DudderidgeRichard HindleyMark EmbertonSimon BrewsterPrasanna SooriakumaranJames W F CattoAmr EmaraHashim AhmedPaul WhybrowSteffi le ConteJenny L Donovan
Published in: BJU international (2018)
Although clinicians find it challenging to recruit patients to a trial comparing different contemporary treatments for prostate cancer, training and support can enable recruiters to become more comfortable with conveying equipoise and providing clearer information to patients.
Keyphrases
  • prostate cancer
  • radical prostatectomy
  • end stage renal disease
  • ejection fraction
  • newly diagnosed
  • prognostic factors
  • patient reported outcomes
  • study protocol
  • phase iii
  • phase ii