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Regional differences in gene regulation may underlie patterns of sensitivity to novel insecticides in Leptinotarsa decemlineata.

Galen P DivelyMichael S CrossleySean D SchovilleNathalie SteinhauerDavid J Hawthorne
Published in: Pest management science (2020)
Our results suggest a mechanism for geographic variation in rates of adaptation to insecticides, whereby baseline levels of gene expression determine a population's response to novel insecticides. These findings have implications for the regional development of insecticide resistance management strategies and for the fundamental question of what determines the rate of adaptation to insecticides. © 2020 Society of Chemical Industry.
Keyphrases
  • aedes aegypti
  • gene expression
  • zika virus
  • dna methylation