Antimicrobial evaluation of the Cynara cardunculus extract in Helicobacter pylori cells using mid-infrared spectroscopy and chemometric methods.
Pedro Sousa SampaioCecília R C CaladoPublished in: Journal of applied microbiology (2022)
MIR-FTIR spectroscopy and chemometric methods allowed to register the biomolecular changes due to the potential antimicrobial drugs at reduced concentrations comparatively to the conventional assay based on an agar-dilution method, being considered a useful approach to develop a platform to discover new bioactive molecules, allowing to reduce time and costs related to the exploratory step.
Keyphrases
- helicobacter pylori
- staphylococcus aureus
- induced apoptosis
- helicobacter pylori infection
- high throughput
- cell proliferation
- cell cycle arrest
- long non coding rna
- oxidative stress
- high resolution
- long noncoding rna
- single molecule
- liquid chromatography tandem mass spectrometry
- signaling pathway
- cell death
- climate change
- ms ms