Key factors associated with 6TGN and 6MMPN concentrations in children treated by thiopurine for acute leukemia and inflammatory bowel disease.

T Adam de BeaumaisS LorrainN MamhoudiM SimoninC Martinez VinsonY MedardA PetitÉvelyne M Jacqz-Aigrain

Published in: British journal of clinical pharmacology (2023)

TDM allowed identification of children who do not reach target levels or remain over treated. Including TDM in follow-up may help physicians to adjust dosage with the aim of reducing adverse effects and improve treatment outcome.

Keyphrases

young adults
primary care
ulcerative colitis
bioinformatics analysis