Canonical Wnt/β-catenin signaling has positive effects on osteogenesis, but can have negative effects on cementogenesis.
Tiancheng LiHan WangYukun JiangYuzhe GuanShuo ChenZuping WuShujuan ZouLynda Faye BonewaldPeipei DuanPublished in: Journal of periodontology (2022)
These findings indicate that Wnt signaling has distinct and different effects on the regulation of long bone as compared with cementum.