High contiguity genome sequence of a multidrug-resistant hospital isolate of Enterobacter hormaechei.
Leigh G MonahanMatthew Z DeMaereMax L CumminsSteven P DjordjevicPiklu Roy ChowdhuryAaron E DarlingPublished in: Gut pathogens (2019)
This study provides important insights into the evolution and potential spread of antimicrobial resistance in a nosocomial E. hormaechei strain. More broadly, it further exemplifies the power of long-read sequencing technologies, particularly the Oxford Nanopore platform, for the characterisation of bacteria with complex resistance loci and large repeat elements.
Keyphrases
- antimicrobial resistance
- multidrug resistant
- single molecule
- acinetobacter baumannii
- klebsiella pneumoniae
- healthcare
- single cell
- genome wide
- drug resistant
- gram negative
- high throughput
- emergency department
- gene expression
- climate change
- dna methylation
- adverse drug
- cystic fibrosis
- staphylococcus aureus
- solid state
- drug induced