Real-time optimization to enhance noninvasive cortical excitability assessment in the human dorsolateral prefrontal cortex.

Sara ParmigianiChristopher C ClineManjima SarkarLily FormanJade TruongJessica M RossJuha GogulskiCorey J Keller

Published in: bioRxiv : the preprint server for biology (2024)

We developed a real-time closed-loop optimization procedure to obtain high amplitude early local TEPs (EL-TEPs) from dlPFC TMS.Sequential optimization of coil angle and brain target reduced artifacts by 63%.Sequential optimization of coil angle, brain target, and intensity increased EL-TEP amplitude by 75%.

Keyphrases

prefrontal cortex
resting state
functional connectivity
endothelial cells
white matter
high resolution
transcranial magnetic stimulation
transcranial direct current stimulation
working memory
multiple sclerosis
magnetic resonance imaging
brain injury