Magnetic-optical dual-modality imaging monitoring chemotherapy efficacy of pancreatic ductal adenocarcinoma with a low-dose fibronectin-targeting Gd-based contrast agent.
Wenjia ZhangXiaolong LiangXinyu ZhangWei TongGuangyuan ShiHaozhuo GuoZhengyu JinZhenyu ZhangYang DuHuadan XuePublished in: European journal of nuclear medicine and molecular imaging (2024)
MRI/FMI with a low dose of ZD2-Gd-DOTA-Cy7 enables sensitive imaging of PDAC and the quantitative assessment of fibrotic changes during AG chemotherapy, which shows potential clinical applications for precise diagnosis, post-treatment monitoring, and disease management.
Keyphrases
- low dose
- high resolution
- high dose
- contrast enhanced
- locally advanced
- magnetic resonance imaging
- magnetic resonance
- pet ct
- squamous cell carcinoma
- cancer therapy
- idiopathic pulmonary fibrosis
- molecularly imprinted
- fluorescence imaging
- risk assessment
- drug delivery
- chemotherapy induced
- high speed
- climate change
- replacement therapy
- liquid chromatography
- simultaneous determination