Immunological Characteristics between αβ TDC and γδ TDC Cells in the Spleen of Breast Cancer-Induced Mice.

Polyana Barbosa Silva Márcia Antoniazi Michelin Millena Prata Jammal Eddie Fernando Candido Murta

Published in: Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia (2021)

Healthy mice engrafted with malignant cells 4T1 breast tumor presented TDC with γδ TCR repertoire. These cells express cytotoxic molecules of lymphocytes T, producing anti-tumor proinflammatory cytokines.

Keyphrases

induced apoptosis
cell cycle arrest
endoplasmic reticulum stress
signaling pathway
cell death
oxidative stress
metabolic syndrome
young adults
pi k akt
skeletal muscle
peripheral blood
high glucose
stress induced