Marked and prolonged serotonin toxicity in a tramadol-poisoned patient with a pharmacokinetic study.

Guillaume BianconiIsabelle MalissinLaurence LabatNihel KhoudourPascal HouzéNicolas PalletBruno MégarbaneXavier Declèves

Published in: Clinical toxicology (Philadelphia, Pa.) (2021)

Marked and prolonged serotonin toxicity was attributed to increased M2 production due to paroxetine- and propranolol-related CYP2D6 inhibition of tramadol metabolism.

Keyphrases

oxidative stress
case report
postoperative pain