Angiopoietin-2 as a marker of endothelial activation is a good predictor factor for intensive care unit admission of COVID-19 patients.

David M SmadjaCoralie L GuerinRichard ChocronNader YatimJeremy BoussierNicolas GendronLina KhiderJérôme HadjadjGuillaume GoudotBenjamin DebucPhilippe JuvinCaroline Hauw-BerlemontJean-Loup AugyNicolas PeronEmmanuel MessasBenjamin PlanquetteOlivier SanchezBruno CharbitPascale GaussemDarragh DuffyBenjamin TerrierTristan MiraultJean-Luc Diehl

Published in: Angiogenesis (2020)

Angiopoietin-2 is a relevant predictive factor for ICU direct admission in COVID-19 patients. This result showing an endothelial activation reinforces the hypothesis of a COVID-19-associated microvascular dysfunction.

Keyphrases

intensive care unit
sars cov
emergency department
endothelial cells
coronavirus disease
mechanical ventilation
oxidative stress
respiratory syndrome coronavirus
extracorporeal membrane oxygenation